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In IIH, use of exenatide to reduce ICP did not have a negative impact on cognition at 12 weeks

By now Holst had joined them as a consultant (Molteni, Chen)

Contraindications and cautions include: Immunocompromised states : Women with HIV/AIDS, those receiving chemotherapy, or taking immunosuppressive medications should consult their specialist before using probiotics, as rare cases of probiotic-related infections have been reported Central venous catheters or other indwelling devices : Risk of bacterial translocation, particularly with Saccharomyces boulardii, which has been associated with fungemia in seriously ill patients Severe acute pancreatitis : Probiotics are contraindicated in this setting Known allergies : Some probiotic products contain dairy, soy, or other potential allergens Drug interactions : There is no evidence of direct pharmacological interactions between probiotics and GLP-1 medications

Yet, these analyses were not adjusted for multiplicity of testing and must be considered hypothesis-generating and interpreted with caution

Electrophysiological recordings revealed that exendin-4 increases the frequency of spontaneous excitatory postsynaptic currents (sEPSCs) of VTA dopaminergic neurons suggesting the possible presynaptic modulation of GLP-1R on glutamatergic terminals

[DOI] [PubMed] [Google Scholar] 84.Dahl-Jrgensen K, Brinchmann-Hansen O, Hanssen KF, Sandvik L, Aagenaes O