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The most successful example of an acylated GLP-1 is liraglutide, which was approved by the FDA in 2010 under the brand name Victoza

Lopez-Delgado MI, Morales M, Villanueva-Penacarrillo ML, Malaisse WJ, Valverde I

The mechanism is not complicated

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While Retatrutide also activates glucagon receptors, limited MASH-specific data exists for this compound

Some scientists even suggest it be used as a supplement to help manage diabetes
