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In patients with T2D with renal impairment, previous research showed that dapagliflozin 10 mg improved weight and systolic pressure, while the benefit on glycemic control was small [38]

Physiol Behav 206:232242 Bruns VN, Tressler EH, Vendruscolo LF et al (2024) IUPHAR review-Glucagon-like peptide-1 (GLP-1) and substance use disorders: an emerging pharmacotherapeutic target

People may turn to patches because they find the idea of weight loss injections to be uncomfortable

The STEP 4 trial showed that participants who discontinued semaglutide regained approximately two-thirds of their lost weight within one year

2017, doi: 10.1038/nature24277
