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We may speculate that a larger reduction of plasma aldosterone in the patients with advanced CKD seen in our study could be caused by a higher local activity of RAAS due to kidney dysfunction

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For those with complex medical histories or questions about combining semaglutide with other medications , the lack of a mandatory consultation could be a drawback

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observed that, in vitro, exendin-4 may promote neurite outgrowth via both the ERK MAPK and the PI3K signaling pathways and may be able to rescue degenerating neurons [77]