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On the other hand, the protein expressions of TIMP1 and TIMP2, two indicators of metalloproteinase inhibitors, displayed an opposite pattern of inflammation among the five groups (Fig

Obesity-related hyperglycemia and hyperlipidemia lead to insulin resistance and chronic inflammation, exposing beta cells to stresses such as inflammation, endoplasmic reticulum stress, oxidative stress, and amyloid stress [20]

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