glp-1 and suicidal ideation Suicide suicide attempt in users of receptor agonists: a nationwide case-time-control study GLP-1 RAs Unlikely to Increase

Because Alzheimers disease and dementia risk are closely connected to insulin resistance, vascular health, inflammation, and metabolic dysfunction, researchers are asking whether GLP-1 signaling may influence brain aging

While patients living with chronic life-threatening conditions like Type 2 diabetes may accept these risks, people using GLP-1 drugs for less life-threatening and severe purposes like obesity may be less forgiving if the side effects outweigh the perceived benefits

Trmper A, Trmper K, Trusheim H, Arnold R, Gke B, Hrsch D

cholecystectomy, cholecystitis, cholelithiasis and cholangitis

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Recent research suggests GLP-1 receptor expression varies across the gastrointestinal tract, with highest concentrations in the colon