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Another SURMOUNT-3 analysis208 demonstrated that tirzepatide improved health-related quality of life scores in obese/overweight adults, with greater benefits observed in those achieving higher weight loss thresholds and in those without baseline functional limitations

doi: 10.1016/j.soard.2018.03.003

Raj H, Durgia H, Palui R, Kamalanathan S, Selvarajan S, Kar SS, Sahoo J

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This occurs in the fasting state where ANGPTL4 is upregulated in WAT while being inhibited in muscle and BAT [104]