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The approval marks the first glucagon-like peptide-1 receptor agonist approved under the Commissioner's National Priority Voucher program

In this trial, the majority of subjects did not have established CVD at baseline, and the highly anticipated results from the trial will add to the body of evidence on the potential role for GLP-1RAs on CV risk reduction in a broad range of individuals with T2D [38]

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This is where the comparison gets more nuanced

Expression of PPAR is also found in hypothalamic nuclei that govern energy metabolism 24 , and viral-mediated overexpression of hypothalamic PPAR decreases food intake in diet-induced obese (DIO) mice 25