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Understanding why fatigue occurs, how long it typically persists, and practical management strategies can help patients navigate this common side effect whilst continuing beneficial therapy for type 2 diabetes or weight management

22 However, the fact that the magnitude and speed of hemoglobin A1c reduction with treatment were identified as risk factors for progression suggests it could be another example of the well-established early worsening phenomenon first observed in type 1 diabetic patients intensively treated with insulin in the Oslo Study, Kroc Collaborative Study and Diabetes Control and Complications Trial