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Description
Acute effects of glucagon-like peptide-1, GLP-1(9-36 amide), and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers
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The fusion product is resistant to DPP-4 degradation, due to an alanine to glycine substitution at position 2 (A2G) in each of the peptide sequences 28,29 , and has a plasma half-life of five days on average in humans 30,31,32

The change of normalized values of LF power in spectral analysis correlated positively with the change of heart rate after liraglutide (r = 0.36, p = 0.037) whereas the change of HF power correlated negatively with the change of heart rate after liraglutide (r = 0.39, p = 0.023)
