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however, human studies have not revealed significant abnormalities with first-trimester exposure

These divergent patterns of -arrestin utilization and endosomal signaling may underlie differences in drug-specific clinical profiles, including glucose control, durability of weight loss, and gastrointestinal tolerability

Wu et al., 2015)

W., Mailhac, A., Lhde, J

In people with symptoms or rapid weight loss, electrolyte testing can provide useful context alongside creatinine and eGFR

Key policy areas that require attention include: Clinical Practice Guidelines : Development of standardized, evidence-based guidelines for the use of GLP-1 RAs in children and adolescents, including indications, dosing, and monitoring