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Lupi et al., (2010), tested the effects of acute (45 min) or prolonged (2 days) exposure to GLP-1 or GIP, alone or in combination on human pancreatic islets, that were obtained from non-diabetic and type 2 diabetic donors

UnferVKandarakiEPkhaladzeLRoseffSVazquez-LevinMLaganAet al

Front Immunol 2023

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Qiao L, Lu C, Zang T, Dzyuba B, Shao J

Additionally, lixisenatide was tested in a large cardiovascular safety trial ( ELIXA , in post-heart-attack diabetic patients) and was found cardiovascularly neutral it neither increased nor decreased CV events versus placebo ( [128] )