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Fear of long-term effects: Given the ongoing discussions about risks in the medical community, some patients may have concerns about the long-term impact of GLP-1 medications, including dangerous adverse reactions as described on the FDA warning label, like acute kidney injury and hypoglycemia

Yuying Luo, MD Medical Reviewer Yuying Luo, MD, is an assistant professor of medicine at Mount Sinai West and Morningside in New York City

Theres even an upcoming phase 2 trial that will study whether GLP-1s affect depressive symptoms in people with major depressive disorder

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Tips for managing mild abdominal pain or discomfort Eat smaller meals and drink plenty of fluids to help aid with digestion