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For those who have tried everything from fasting to feasting, we now have a solution that works directly on hunger hormones

Plateaus can result from metabolic adaptation, dietary drift (gradually eating more without realizing it), reduced physical activity, or reaching a new set point

A diabetic state also leads to a decreased population of endothelial progenitor cells from the bone marrow

Most GLP-1 medications only target one hormone

Primary care is typically best positioned to lead longitudinal prevention - screening for hypertension, T2DM, dyslipidemia, chronic kidney disease, smoking, and alcohol use

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