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Conclusion: guidelines and biomarkers react to new therapies Guidelines are beginning to incorporate the wealth of new treatments, and biomarkers could further help refine clinical practice in MG

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2 Molecular and cellular mechanisms of GLP-1 2.1 Metabolic regulation of glucose homeostasis The classical pathophysiological mechanisms of GLP-1 have been well studied

Patients on testosterone therapy who are interested in trial participation should inform their prescribing clinician and search for eligible UK studies via the NIHR 'Be Part of Research' portal

Gillian Murray, MPharm, PG Dip, Clin Pharm, INP

Insulin-induced lipoatrophy: evidence for an immune pathogenesis