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While many on the medications said they have changed their lives for the better, some experts are concerned about the long-term effects of these relatively new drugs. Once its approved on the market, theyll collect data for like, a year, and thats it, said Alexis Moore, assistant professor of Physician Assistant studies and a clinician by training

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In a 10-week, once-daily, multiple-dose trial, 84 healthy males received 20 or 40 mg oral semaglutide (with 300 mg SNAC), placebo, or placebo with SNAC, and 23 males with type 2 diabetes (T2D) received 40 mg oral semaglutide (with 300 mg SNAC), placebo, or placebo with SNAC