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doi: 10.1530/EJE-10-1096 48 GonzalezBVargasGEspinosa de los MonterosALMendozaVMercadoM

Although speculative, we assume that after short exposure of artery to hyperglycemia and/or hypercholesterolemia, GLP-1 receptor increases to protect artery initially, but that after chronic exposure to them, such protective pathway does not appropriately function

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Rapid weight loss and milk quality When the body loses weight rapidly, it mobilizes stored fat

Type 2 diabetes

Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation