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These agents target multiple hormone pathways involved in appetite regulation, insulin secretion, energy expenditure, and hepatic metabolism

Individuals utilizing GLP-1 medications such as Ozempic and Wegovy navigate a specific set of nutritional demands, primarily centered around maximizing protein intake to prevent muscle loss while managing overall calorie consumption

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Methods This is a cohort study combining several population-wide databases and covering a Spanish population of five million inhabitants, including all adults with obesity who initiated treatment with either GLP-1RA or SGLT-2i for type 2 diabetes from 2015 to 2021

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