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In the 2026 survey 73.9% (249/337 [95% CIs 69.0-78.4%]) of patients who are eligible for a GLP-1RA who have not used these a GLP-1RA and have expressed an interest in participating in a clinical trial of a GLP-1RA

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Clinical trials assessing GLP-1 RAs for weight loss rarely report facial fat loss as an adverse effect

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We subsequently developed an in vivo technique to assess gut hormone release into the portal vein following colonic infusion of propionate

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