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ELIXA trial included patients with recent cardiovascular event (patients with acute coronary syndrome 180 days before randomization), and although there was no benefit in MACE reduction in lixisenatide treated patients compared to placebo, results revealed cardiovascular safety of lixisenatide in this specific high risk population (38, 40)

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[DOI] [Google Scholar] [33].Kuitunen I

Because weight loss is complex and affects everyone differently, the length of time it takes for a patient to feel or see a difference in their appetite or weight will vary.