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Reddit discussion is mixed: Many patients praise pricing and effectiveness, while others cite customer service complaints, medication shortages, and pharmacy concerns

doi:10.1038/nature22378 82

GIPR agonists In contrast to the results inferred from the obesity-promoting effects of GIP, it has been shown that transgenic mice overexpressing GIP exhibit a significant decrease in weight gain after ingestion of an HFD, suggesting that chronic elevation of GIP levels well above physiological concentrations may exert a centrally mediated suppressive effect on appetite [124]

Lord J, Thomas R, Fox B, et al

In phase 3 trials, peak increases in serum creatinine were observed after 4 to 8 weeks of treatment

Matt Kaeberlein, the Chief Executive Officer of Optus Span Inc., an affiliate professor at the University of Washington, and a co-founder of the Dog Aging Project