how were glp 1 agonists discovered Glucagon-like peptide-1 Frontiers | GLP-1 receptor agonists:
Description
Jorsal A, Kistorp C, Holmager P, et al
Importantly, this increase in insulin happens only when glucose levels rise (i.e., when the body needs insulin)
Why would activating it benefit metabolic research
Figure 35: Diagram showing action of GLP-1, GIP (incretins) and DPP-4 inhibitors, credit: Ilmari Karonen, Wikimedia
Its robust evidence
Heerspink HJ, Perkins BA, Fitchett DH, et al
