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Quick Answer: Weight loss injections, specifically GLP-1 receptor agonists, do lower cholesterol by reducing triglycerides 15-25%, decreasing LDL cholesterol 3-7%, and modestly increasing HDL cholesterol

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Prefer needle-free options: Shed lists non-injectable GLP-1 formats including drops, lozenges, and oral tablets on its weight-loss category page

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While Oprah obviously cares about her personal health, this People story is part of a broader marketing blitz to grab attention, get people on-platform (ESPECIALLY with the new year almost here, new weight loss goals you guys!!) , and destigmatize the shame around the obesity conversation