microdosing glp-1 reddit Interview with Dr. Tyna Moore, ND, DC — What Women Need to Know About Microdosing, Peptides, Gut Health, and Hormonal Optimization Study Reveals Unknown GLP-1 Side

10.1007/s40262-021-01025-x 12 PechenovS.RevellJ.WillS.NaylorJ.TyagiP.PatelC.et al (2021)

A sustained 14 mmHg reduction in systolic pressure translates to roughly a 40 to 50% reduction in stroke risk and a 20 to 30% reduction in coronary events over the long term

Key tips for underwriting applicants with GLP1 use Immediately look for: Evidence of the underlying diagnosis (as seen in medical claims, EHR, APS) Whether the GLP-1 is FDA-approved or off-label for that condition Signs of medication adherence (12 months, regular fills) Get cautious when: A GLP1 appears without any supporting clinical context Fills are intermittent or recently initiated Theres no alignment between the medication and expected companion therapies (e.g., no CPAP with sleep apnea) Be confident when: The diagnosis is clear The drug is first line and clinically appropriate Use has been stable long enough to confer benefit Kyle Schimek, PharmD Kyle Schimek is a board-certified pharmacist and Clinical Services Manager at Milliman IntelliScript

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doi: 10.1056/NEJMOA1603827 37 LeRNguyenMTAllahwalaMAPsaltisJPMaratheCSMaratheJAet al

Secondary outcomes included the individual components of the composite outcome and pancreatic cancer