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Knudsens work found that liraglutide was internalized by proopiomelanocortin (POMC)/cocaine- and amphetamine-regulated transcript (CART) neurons and indirectly inhibits neuropeptide Y (NPY) and agouti-related peptide (AgRP) neurons through Gamma Amino Butyric Acid (GABA) dependent signaling

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Hepatology 60 , 565575 (2014)

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While some patients report anxiety on tirzepatide , it is far less common and typically related to the adjustment period rather than a direct pharmacological effect

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Check out our master breakdown on Pepcid vs Prilosec for GLP-1 Acid Reflux to learn about the "PPI Trap" and find safe, fast-acting relief

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