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A recent trial on the treatment effect of semaglutide in people with obesity reported the significant effects of the long-acting GLP-1RA semaglutide on body weight and related phenotypes (169)

Severity : It can vary in intensity but often subsides with time

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The Effects Of GLP-1 Agonists On HbA1c And Insulin Dose Among Patients With Type 1 Diabetes

However, to ensure maximum efficacy, we strongly advise refrigerating the vial as soon as you have the opportunity, and using an insulated bag and cold packs to help to keep the medicine within the correct temperature range when refrigeration isnt available