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The scale may show initial weight loss, and you may also notice your clothes fitting differently even before the scale moves significantly

Palnaes Hansen C, Andreasen JJ, Holst JJ (1997) The release of gastric inhibitory peptide, glucagon-like peptide-I, and insulin after oral glucose test in colectomized subjects

Conclusion GLP-1 constipation is a common and understandable side effect of how these medications work

There is also a simpler explanation

PubMed Objective: Although the pathogenesis of non-alcoholic fatty liver disease (NAFLD) has been extensively studied, the role of its underlying pathogenesis remains unclear, and there is currently no approved therapeutic strategy for NAFLD