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Interestingly, the expression of GLP-1 seems to be substantially higher in the lung compared to other organs, prompting further efforts to understand the role of GLP-1R in the lung [4]

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But when doctors do prescribe them for overlapping metabolic issues (such as insulin resistance or obesity), the most commonly recommended medications include: Semaglutide (Ozempic/Wegovy) Tirzepatide (Mounjaro/Zepbound) technically a GLP-1 + GIP dual agonist Liraglutide (Saxenda) The choice depends on: How severe metabolic symptoms are Tolerance to side effects Cost and insurance status The clinicians expertise One study looking at GLP-1associated fat changes noted that visceral fat reduction can significantly improve inflammatory biomarkers, as shown in an adipose tissue study