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Description
Reduced Risk of Cardiovascular Events Some GLP-1 medications have shown benefits in reducing the risk of major cardiovascular events

DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity

These cardiovascular advantages have made GLP-1 medications a preferred choice for type 2 diabetes patients with established cardiovascular disease

However, rodent studies suggest a link to medullary thyroid cancer, leading to contraindications for individuals with a personal or family history of MEN2A or medullary thyroid cancer [13]

Fewer than half of employer plans cover weight-loss drugs Wegovy and Ozempic are glucagon-like peptide-1 drugs, or GLP-1s, that suppress the appetite of users, leading to weight loss

They noted that many southern states with high prevalence rates of obesity also have higher prescription fill rates for GLP-1s