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These are the conclusions of an observational study published in Nature Medicine

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These include dietary interventions, orlistat, lorcaserin, phentermine/topiramate, glucagon-like peptide-1 receptor agonists, dipeptidyl peptidase-4 inhibitors, pramlintide, dapagliflozin, the duodenaljejunal bypass liner, gastric pacemakers and gastric balloons

Thirteen trials involving 5,807 participants were identified

Nausea affects many semaglutide users, particularly during dose escalation

While lifestyle changes remain important, many people found that traditional approaches didnt always produce sustainable outcomes