what are the potential side effects of glp-1 drugs Weight-Loss Medication and How to Manage Them Long-term Success of GLP-1s Hinges
Description
Acute DPP-4 inhibition modulates vascular tone through GLP-1 independent pathways
Most studies were judged to have a low risk of bias, but a few studies however showed moderate risk of bias
These second order effects will become more far reaching as insurance coverage becomes wider for these drugs - this will be the differentiator between the risk/reward being better on the first-order beneficiaries (LLY and NVO) and the second-order plays like short bariatric surgery/sleep apnea/gyms/fast food & CPG
The involvement of the Ca +2 / CaM kinase II pathway, which is mediated by G protein-coupled receptor family C group 6 subtype A, was determined to be responsible for this elevation
Kim W, Egan JM
J Biol Regul Homeost Agents
