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24 Patients had a mean age of 60 years, mean diabetes duration of 4 years, mean A1C of 6.99%, and BP 132/79 mmHg

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References 1.Campbell JE, Drucker DJ

It should come as no surprise that GLP-1 has pleiotropic effects beyond reducing glucose levels, considering the widespread distribution of GLP-1R

51 Gallbladder Disease Rapid weight loss can increase the risk of cholelithiasis and cholecystitis, and was observed in major GLP-1RA trials

27,36 In a controlled study, 63 patients with type 2 diabetes and a lower-extremity ulcer were randomized to either saxagliptin 5 mg or placebo daily