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Keywords: glucagon-like peptide-1, hypothalamic-pituitary-adrenal (HPA) axis, sympathetic nervous system (SNS), ion channels, food intake 1
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The SURMOUNT-1 trial evaluated tirzepatide specifically for chronic weight management in adults without diabetes

Abstract Glucagon-like peptide-1 (GLP-1) enhances meal-related insulin secretion, which lowers blood glucose excursions
