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New Engl J Med (2022) 387(3):20516

some patients find that injecting in the evening reduces daytime nausea, though this should be discussed with a healthcare provider

Reconstituting 10mg retatrutide with bac water is a delicate process that requires patience and a gentle touch

No more frustration with approaches that don't work

Cracks in the cartridge, a loose or damaged needle attachment site, or a pen that has been dropped from significant height may have internal damage affecting dose accuracy

The SURMOUNT-5 trial , as described by Aronne and colleagues, compared tirzepatide (Zepbound) to semaglutide (Wegovy), a mono GLP-1, in 751 adults living with obesity with one weight-related medical issue but without diabetes