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Many patients find that injecting in the evening and eating a small meal before bed reduces morning nausea compared to daytime injections

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Observation periods included the in-trial period (time from week 0 to date of last contact with trial site) and the on-treatment period (administration of any dose of trial product within the prior 14 days [prior 49 days for adverse event evaluation])

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Most natural GLP-1 hormones disappear from the body within minutes

However, studies conducted concurrently showed unexpected superiority of once-weekly forms of GLP-1 drug candidates to daily forms, and raised questions as to whether the addition of GIP was necessary for a useful incretin agonist