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In vitro studies have shown that both propionate and butyrate increase GLP-1 and PYY secretion by L-cells via G-protein-coupled receptor 43 (GPR43) human receptor stimulation in a dose-dependent way, regulating food and energy intake [54]

GO:0030100), adipose tissue development (GO:0060512)

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These symptoms can lead to dehydration and electrolyte depletion, particularly in vulnerable individuals

Acknowledgments The author is grateful to the communities of structural biology, biophysics, medicinal and computational chemistry and algorithm design, for the continued accumulation of knowledge and data for drug discovery & design, and for the continued development of tools (hardware, software and algorithm) for drug discovery & design.

Food and Drug Administration (FDA) approved drugs for specific uses