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Alternatively, the Microdose GLP-1 Protocol at $129/month uses a slower titration schedule designed to minimize neurological side effects while still supporting weight loss

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ESPE Abstracts Clment K, van den Akker E, Argente J et al (2020) Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials

The results of the adjusted data reflected those following stratification, with only minimal differences