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If patients saw a significant amount of weight loss and saw their joint pains improve, or their sleep apnea improve [because of it], all of those comorbidities will get worse as the weight comes back, she says

It is entirely reasonable to ask your healthcare professional about the latest evidence on investigational agents

These new drugs like retatrutide may get more robust results for those who have already tried and failed

If a patient stops the medication, diabetes will relapse (if it was controlled, not cured) and weight will likely be regained, as evidenced by trials where cessation led to weight regain trends

How Gallbladder Removal Affects Bile Acid Signaling and GLP-1 Response The gallbladder stores and concentrates bile acids needed for fat digestion
