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Both medicines are given as shots under the skin once weekly using a pen-like device

Mller TD et al

Vomiting affected 31% of high-dose participants, while diarrhea occurred in 23% of patients
These reported symptoms may include skin dryness, fatigue, mood changes, hormonal concerns, or other physical complaints

It is generally well-tolerated but should be used with caution in individuals with a history of pancreatitis
