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New data presented at the ASCO Gastrointestinal Cancers Symposium 2026 have further strengthened the hypothesis that metabolic modulation may represent a new frontier in colorectal cancer prevention

Best Pract Res Clin Gastroenterol (2010) 24(5):695708

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[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Duffy A

Beyond the M2-polarization function, GLP-1R activation also supports macrophage migration, which may be mediated by its regulation of macrophage polarization and the effects of IL-6 [93, 94]

The individual underwent multiple tests including upper and lower endoscopies, a hepatobiliary iminodiacetic acid (HIDA) scan, abdominal Doppler blood flow study, as well as multiple medications to relieve the gastroparesis symptoms