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Blood pressure: Systolic BP reduction of ~17 mmHg, clinically relevant in patients with cardiometabolic risk

On December 14, 2023, "Science" magazine announced the top ten scientific breakthroughs of the year

Clinical audiences are equally impressed with the data, hailing a new era for how obesity is perceived and treated, notwithstanding the missed statistical significance for cardiovascular death and the other secondary confirmatory endpoints not being tested for superiority as a consequence

In the age of GLP-1s, supplement companies face additional complexities on what they can and cannot say about weight management claims.

Orforglipron, Lillys first small-molecule oral GLP-1 receptor agonist in Phase 3, showed meaningful weight loss and glycemic control in adults with type 2 diabetes and overweight or obesity

Intensifying competition among a growing API supplier base (check the first comment below for details) 2