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A key issue for payers and users of these medications is whether those who use them can eventually maintain lower weights without continued reliance on these medications

These medications are contraindicated during pregnancy due to potential fetal risks demonstrated in animal studies, and your provider will guide appropriate prenatal care

Unintentional weight loss exceeding expected therapeutic goals, or inability to maintain adequate nutritional intake, requires assessment for excessive medication effect or other underlying conditions

GLP-1 medications carry serious gastroparesis risks that extend far beyond commonly reported nausea and vomiting, requiring heightened clinical awareness and proactive management strategies

They treat diabetes and metabolic risk factors

Because GLP-1 relies upon your bodys own insulin to have this effect, GLP-1 isnt used when your pancreas cant make insulin, such as in patients in type 1 diabetes