what is glp-1 good for Weight Loss NYC What is GLP-1? Benefits, Uses
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Certain oral GLP-1s need to be taken on an empty stomach with specific timing

The fact that this can be taken so easily is incredibly important. For some patients, the appeal is simple avoiding needles

This definitely impacts incentives (i.e., an insurance company might lose money on a surprise increase of GLP1 costs but make money on the PBM rebates)
Full publication of combination-therapy data is awaited, however interim analysis from the phase II COURAGE trial (NCT06299098) found 3.3% reduction in lean mass of obese patients treated with the combination of trevogrumab and semaglutide, compared with 6.5% reduction with semaglutide alone [70]

Bendotti et al
