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5.4 Gastrointestinal Side Effects and Nutrient Loss Nausea and vomiting are well-documented adverse effects. Persistent vomiting or diarrhoea may: Increase electrolyte loss Reduce caloric intake Reduce dietary diversity However: These effects are typically transient and dose-related

Clinical trials show that meaningful percentage weight loss often develops over several months, especially when medication is paired with diet and activity changes

Retatrutide activates GLP-1 receptors, GIP receptors, and glucagon receptors simultaneously

Monitor yourself for increased appetite suppression or mild nausea over the next few days

Wegovy is licensed in the UK for weight management in adults with a body mass index (BMI) of 30 kg/m or greater, or 27 kg/m or greater with at least one weight-related comorbidity

At-home GLP-1 injections: A how-to guide