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The glycine and B12 additions are generally well-tolerated at the doses used in these formulations and rarely contribute their own adverse effects

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It is possible that some of those patients were in honeymoon period, or had an alternative diagnosis, such as ketosis-prone diabetes or latent autoimmune diabetes in adults (LADA)

J Neurosci Res (2003) 72(5):60312

18, 2025, by Lindsey Shapiro, PhD Fact-checked by Marta Figueiredo, PhD The wide range of possible Prader-Willi syndrome (PWS) symptoms include excessive hunger, low muscle tone, learning and behavioral issues, and distinct physical features

The only study was conducted on rats and explicitly states it cannot guide human dosing