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Pyridoxine (Vitamin B6) Sometimes, Vitamin B6 is added to help with nausea, which is a frequent side effect for those starting semaglutide

The most common motivation is convenience and comfort: injections require weekly self-administration and sometimes refrigeration, which can feel inconvenient or uncomfortable for some individuals, especially those who dislike needles or managing cold storage

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Regulatory agencies, including the FDA and EMA, have issued warnings about vision loss, stomach problems and risks from unapproved or compounded versions