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Fourthly, while the intestine is the dominant source of circulating serotonin, future studies will be required to determine whether intestinally derived serotonin is the mediator of metabolic and hormonal changes characteristic of PBH and whether neural signaling is required

[DOI] [PubMed] [Google Scholar] 546.Jhala U.S., Canettieri G., Screaton R.A., Kulkarni R.N., Krajewski S., Reed J

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It means that use of semaglutide is probably not a permanent fix