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These trials demonstrated dose-dependent improvements in glycemic control and notable weight reduction, prompting further investigation at the 0.5 mg and 1.0 mg maintenance doses

diabetic ketoacidosis (leads to changes in blood pH)

at which points there were 102 subjects), a cohort study published in JAMA Network Open in 2022 found

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Patients should be aware of warning signs and seek medical advice if severe or unusual symptoms develop during treatment