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That same year, Zafgen demonstrated beloranibs efficacy, a MetAP2 inhibitor, in a Phase III trial, but safety concerns ultimately led to its discontinuation

Meregnani, J

A daily dose of 1000 to 2000 IU covers most needs, though testing can identify if higher doses are appropriate

Older weight loss injections are also available but are less effective and require more frequent dosing, making them rarely worth considering today

They don't seem like they're that big of a thing to do, but to [00:03:00] us, they are huge

So the science is there