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[DOI] [PMC free article] [PubMed] [Google Scholar] 162.Rao Z, et al

Over the course of the study, participants receiving retatrutide experienced substantial average reductions in body weight compared with placebo

Scientists suspect GLP-1s may be a promising antidote for addiction, affecting the brains reward circuitry and modulating dopamine, glutamate, and GABA involved in craving and reinforcement

Patients with disc-at-risk anatomy or vascular risk factors should be counseled about NAION symptoms, while current data on AMD and retinal vein occlusion do not justify altering GLP-1 therapy

Interestingly, GIP affects glucagon differently than GLP-1
